Palladius of Thessalonica was a Byzantine monastic who, according to the synaxarion, was born in Thessalonica and pursued the ascetic life in Alexandria toward the end of the sixth and the beginning of the seventh century. He is numbered among the venerable (monastic) saints and is commemorated on November 27.
Little detailed biography survives. The tradition preserves the essential outline of his life: a native of Thessalonica who left to contend in asceticism in Egypt, where Alexandria and its surrounding desert had long been a center of Christian monastic struggle. The liturgical texts associated with his memory describe a life ordered toward God through prayer and fasting, holding him up as an example of virtuous deeds to the faithful.
The hymnography for the saint is modest in scale: his Service is appointed to be sung at Compline rather than at the principal offices, reflecting the comparatively limited place his commemoration holds in the calendar. The synaxarion is careful to distinguish him from the better-known fourth-century Palladius of Galatia (commemorated January 28), the author of the Lausiac History, the celebrated collection of lives of the Egyptian ascetics.